Type 3c Diabetes

Finally, a treatment for this challenging pancreatogenic condition.

What is type 3c diabetes?

Type 3c diabetes mellitus (T3cDM), or “Pancreatogenic” diabetes is classified by the American Diabetes Association and by the World Health Organization as diabetes due to impairment in pancreatic endocrine function related to pancreatic exocrine damage due to acute, relapsing and chronic pancreatitis (of any etiology), cystic fibrosis, hemochromatosis, pancreatic cancer, and pancreatectomy, and as well rare causes such as neonatal diabetes due to pancreatic agenesis. It is characterized by severe, erratic, and difficult to control, swings in glycemia.
Pancreatic disease or other damage to the pancreas can impact its ability to produce hormones. This includes not only islet β-cell secretion of insulin but also counterregulatory glucagon secretion from islet α-cells and pancreatic polypeptide section from PP-cells such that doses of insulin to control glycemia can unpredictably lead to episodes of severe hypoglycemia. Pancreatic exocrine insufficiency is also a defining characteristic of type 3c and results in malnutrition and nutrient deficiencies.

Previously underdiagnosed, it is now understood that approximately 9% of all diabetes cases are type 3c, and as much as 15-20% in India and Southeast Asia. While not well-known in the general public, this indicates the incidence of type 3c is higher than type 1 diabetes. It is also more severe than either type 1 or type 2 diabetes. The mortality rate for type 3c diabetes is 73 times higher than for type 2. Yet despite these alarming numbers, there are no dedicated treatments available that address the unique, complex challenges of type 3c diabetes.  Until now. 

Growing numbers

The reported incidence of type 3c diabetes has tripled over the past decade.


8-9% of all diabetes cases estimated to be type 3c and as much as 15-20% in India and Southeast Asia.

Devestating Consequences

Mortality rates for type 3c diabetes is 73 times higher than it is for type 2 diabetes.

Contact Us

Thank you! Your message has been sent.
Unable to send your message. Please fix errors then try again.

info at metabolytic dot com


Santa Fe, New Mexico and Los Angeles, California